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Rastislav Jendželovský Selected Research

Proadifen

1/2016Proadifen sensitizes resistant ovarian adenocarcinoma cells to cisplatin.
10/2015Downregulation of BCRP and anti-apoptotic proteins by proadifen (SKF-525A) is responsible for the enhanced mitoxantrone accumulation and toxicity in mitoxantrone-resistant human promyelocytic leukemia cells.
9/2012Inhibition of GSK-3β reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells.

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Rastislav Jendželovský Research Topics

Disease

22Neoplasms (Cancer)
05/2022 - 09/2012
5Colonic Neoplasms (Colon Cancer)
08/2020 - 04/2011
5Breast Neoplasms (Breast Cancer)
01/2019 - 10/2014
4Carcinoma (Carcinomatosis)
04/2021 - 01/2016
3Colorectal Neoplasms (Colorectal Cancer)
04/2021 - 01/2017
3Adenocarcinoma
03/2020 - 01/2016
2Inflammation (Inflammations)
01/2020 - 01/2015
2Leukemia
01/2019 - 10/2015
2Carcinogenesis
06/2016 - 11/2014
1Hypoxia (Hypoxemia)
04/2021
1Brain Injuries (Brain Injury)
01/2020
1Cognitive Dysfunction
01/2020
1Ovarian Neoplasms (Ovarian Cancer)
01/2016
1Adenocarcinoma of Lung
01/2016
1Necrosis
01/2016
1Fever (Fevers)
01/2015
1Pain (Aches)
01/2015

Drug/Important Bio-Agent (IBA)

10hypericinIBA
08/2020 - 04/2011
71-phenyl-3,3-dimethyltriazene (PDT)IBA
05/2022 - 04/2011
6Proteins (Proteins, Gene)FDA Link
08/2020 - 10/2014
5Pharmaceutical PreparationsIBA
04/2021 - 09/2012
5ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2019 - 10/2014
3Type I DNA Topoisomerases (Topoisomerase I)IBA
02/2021 - 08/2015
3Biological ProductsIBA
01/2017 - 04/2015
3ProadifenIBA
01/2016 - 09/2012
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2016 - 04/2011
2SurvivinIBA
08/2020 - 01/2016
2MelatoninIBA
01/2020 - 06/2016
2hyperforinIBA
06/2019 - 12/2012
2multidrug resistance-associated protein 1IBA
01/2019 - 10/2014
2Antineoplastic Agents (Antineoplastics)IBA
01/2017 - 01/2016
2Cisplatin (Platino)FDA LinkGeneric
01/2016 - 10/2014
2Mitoxantrone (Novantrone)FDA LinkGeneric
10/2015 - 10/2014
1Cholinesterases (Cholinesterase)IBA
04/2021
1skyrinIBA
04/2021
1TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
04/2021
1CoumarinsIBA
02/2021
1Tacrine (Cognex)FDA Link
02/2021
1coumarinIBA
02/2021
1Topoisomerase InhibitorsIBA
02/2021
1Oxaliplatin (Eloxatin)FDA LinkGeneric
08/2020
1manumycinIBA
08/2020
1Caspase 3 (Caspase-3)IBA
08/2020
1Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
03/2020
1Free Radical ScavengersIBA
01/2020
1Hormones (Hormone)IBA
01/2020
1Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
06/2019
1Adenosine Triphosphate (ATP)IBA
01/2019
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2019
1ChromatinIBA
01/2017
1Histone Deacetylase InhibitorsIBA
01/2017
1Therapeutic UsesIBA
01/2017
1Volatile Fatty AcidsIBA
01/2017
1Anti-Bacterial Agents (Antibiotics)IBA
01/2017
1EnzymesIBA
01/2017
1anthraceneIBA
06/2016
1PrebioticsIBA
06/2016
1methylureaIBA
06/2016
1InulinFDA Link
06/2016
1CarcinogensIBA
06/2016
1oligofructoseIBA
06/2016
1LigandsIBA
05/2016
1Biomarkers (Surrogate Marker)IBA
01/2016
1sepantroniumIBA
01/2016
1Inhibitor of Apoptosis ProteinsIBA
01/2016
1Apoptosis Regulatory ProteinsIBA
10/2015
1Mixed Function Oxygenases (Monooxygenases)IBA
10/2015
1AcridinesIBA
08/2015
1Drinking WaterIBA
07/2015
1Bromodeoxyuridine (BrdU)IBA
07/2015
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2015
1Messenger RNA (mRNA)IBA
11/2014
1Celecoxib (Celebrex)FDA Link
11/2014
1Methylnitrosourea (N-Methyl-N-nitrosourea)IBA
11/2014
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
11/2014
1ResveratrolIBA
11/2014
1Growth Differentiation Factor 15IBA
11/2014
1Indicators and Reagents (Reagents)IBA
11/2014
1AristoforinIBA
12/2012
1Photosensitizing Agents (Photosensitizers)IBA
04/2011

Therapy/Procedure

8Photochemotherapy (Photodynamic Therapy)
05/2022 - 04/2011
3Drug Therapy (Chemotherapy)
05/2022 - 01/2015
1Aftercare (After-Treatment)
04/2021